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HtrA Serine Peptidase 2 (HTRA2) (Middle Region) Peptide

HTRA2 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN5511274

Quick Overview for HtrA Serine Peptidase 2 (HTRA2) (Middle Region) Peptide (ABIN5511274)

Target

HTRA2 (HtrA Serine Peptidase 2 (HTRA2))

Origin

Human

Source

  • 1
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    Middle Region

    Sequence

    VTPDTRTREA SENSGTRSRA WLAVALGAGG AVLLLLWGGG RGPPAVLAAV

    Characteristics

    This is a synthetic peptide designed for use in combination with anti- HTRA2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    HTRA2 (HtrA Serine Peptidase 2 (HTRA2))

    Background

    This gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined.

    Alias Symbols: OMI, PARK13, PRSS25

    Protein Size: 377

    Gene ID

    27429
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